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The Life of Blood: A rare behind-the-scenes look at the journey that starts with a Dundee donation

When a donor has handed over their life-saving bag, the process has only just begun.

Claire Milne, 25, from Arbroath, giving a whole-blood donation at Dundee Blood Donor Centre in Ninewells Hospital.
Claire Milne, 25, from Arbroath, giving a whole-blood donation at Dundee Blood Donor Centre in Ninewells Hospital. Image: Steve Brown/DC Thomson.

In Dundee, 357 donations of blood are needed weekly to ensure that our hospitals have enough supplies to meet their needs.

In Scotland the figure is 3,300.

Across three regional sites, with five donor centres, the Scottish National Blood Transfusion Service (SNBTS) works to ensure donors are given the opportunity to give blood and help save a life.

Donors Imogen Clark and Justyna Zonko, both Dundee, completing the pre-donation questionnaire at Dundee Blood Donor Centre in Ninewells Hospital.
Donors Imogen Clark and Justyna Zonko, both Dundee, completing the pre donation questionnaire at Dundee Blood Donor Centre in Ninewells Hospital. Image: Steve Brown/DC Thomson.

As a donor myself, I have often wondered what happens with your blood once you have donated, normally around 470ml (1 pint). This amount has the capacity to save up to three lives.

When your donation is complete, the journey for your blood has only just begun.

Here is a rare, behind-the-scenes look, at that process.

Claire Milne, donating at Dundee Blood Donor Centre in Ninewells Hospital.
Claire Milne, donating at Dundee Blood Donor Centre in Ninewells Hospital. Image: Steve Brown/DC Thomson.

Claire Milne, 25, from Arbroath, is a student paramedic.

She spoke to The Courier at Dundee Blood Donor Centre in Ninewells Hospital while giving a whole-blood donation.

“I’ve been giving blood for a few years now because it’s one of the easiest ways to help people that need it the most,” said Claire.

‘How vital blood can be’

“It’s important to me because I know just how vital blood can be in treatment and care.

“I would encourage everyone who is eligible to donate as it is quick and painless, and the staff are always lovely and caring, and a bonus is the free biscuits after.”

Senior charge nurse Cat Durning looks after social work student Sarah Jones, 20, from Dundee, as she donates at Dundee Blood Donor Centre in Ninewells Hospital.
Senior charge nurse Cat Durning looks after social work student Sarah Jones, 20, from Dundee, as she gives her whole blood donation at Dundee Blood Donor Centre in Ninewells Hospital. Image: Steve Brown/DC Thomson.

Social work student Sarah Jones, 20, from Dundee, started donating because of a family member.

She said: “I give blood because I know that so many people need it and rely on it.

“My sister was born three months premature, and she needed blood.

“I feel like it’s a requirement for me to do given the fact so many others gave blood to her.

‘It is very fast is practically painless’

“I suggest everyone who can donate does. It takes 30 minutes and is very fast and practically painless.”

On their journey, blood donations are collected and taken to the Jack Copland Centre in Edinburgh for processing into their separate components.

The Jack Copland Centre, Edinburgh.
The Jack Copland Centre, Edinburgh. Image: Steve Brown/DC Thomson.
Jason McCarthy, 45, at the Jack Copland Centre, Edinburgh.
Jason McCarthy, 45, at the Jack Copland Centre, Edinburgh. Image: Steve Brown/DC Thomson.

These are red blood cells, platelets and plasma.

Red blood cells help patients who are anaemic; platelets, patients who have bone marrow failure, have had chemotherapy, or undergone a transplant; and white blood cells, patients who may be affected by life-threatening infections and are not responding to antibiotics.

One whole-blood donation alongside bags of red blood cells, buffy coat and plasma.
One whole-blood donation, left, alongside bags of red blood cells, buffy coat and plasma. Image: Steve Brown/DC Thomson.

Then there is plasma, part of your blood that carries platelets, red, and white blood cells around the body.

It also contains antibodies, which can be made into medicines for patients with immune disorders and rare diseases.

Centrifuge

Whole-blood donations are placed in a centrifuge, a machine which spins the bags, separating plasma at the top and red cells at the bottom.

A Hettich Centrifuge is used to 'spin down' whole-blood donations before placing on the blood separator, leaving plasma at the top and red cells at the bottom.
A Hettich Centrifuge is used to ‘spin down’ whole-blood donations before placing on the blood separator, leaving plasma at the top and red cells at the bottom. Image: Steve Brown/DC Thomson.
A Hettich Centrifuge.
A Hettich Centrifuge. Image: Steve Brown/DC Thomson.
A blood bag once the centrifuge process is complete, showing plasma at the top and red cells at the bottom.
A blood bag once the centrifuge process is complete, showing plasma at the top and red cells at the bottom. Image: Steve Brown/DC Thomson.

The blood bags go through filtration, which is the removal of white cells to reduce the likelihood of transfusion rejection by the patient.

Leucodepletion or filtration being used to remove white cells form donations to reduce the likelihood of transfusion rejection.
Leucodepletion or filtration being used to remove white cells form donations to reduce the likelihood of transfusion rejection. Image: Steve Brown/DC Thomson.
Leucodepletion in action.
Leucodepletion in action. Image: Steve Brown/DC Thomson.

For newborns and babies there are special Pedi-packs, which hold much smaller volumes, around 70ml.

Pedi-packs for babies.
Pedi-packs for babies. Image: Steve Brown/DC Thomson.

Plasma makes up 55% of human blood, making it the single largest component.

Clotting factors

It contains antibodies, water and proteins called clotting factors, which stop the bleeding if you cut yourself for instance.

Plasma is weighed and volume placed on the label.
Plasma is weighed and volume placed on the label. Image: Steve Brown/DC Thomson.

People like Ron Buist, 69, from Arbroath, also donate their plasma.

He told The Courier: “I started to give blood at Dundee Royal Infirmary when I was at school at the age of 18.

Patients

“Over the years as a nurse in neurosurgery I looked after patients who required blood or plasma.

“I had a family member who required blood products during treatment for cancer.

“I would encourage anyone who is fit and healthy to consider becoming a blood donor. It could help someone at a time of need, and you can feel good that you have helped.”

Ron Buist, 69, from Arbroath, donating plasma on the Aurora machine, watched over by Apheresis donor carer Angela at Dundee Blood Donor Centre in Ninewells Hospital.
Ron Buist, 69, from Arbroath, donating plasma on the Aurora machine, watched over by Apheresis donor carer Angela at Dundee Blood Donor Centre in Ninewells Hospital. Image: Steve Brown/DC Thomson.

Plasma, once separated, is stored below -25C in a blast freezer within one hour of arrival, to preserve the clotting factor.

Plasma is stored in the blast freezer within an hour of arrival.
Plasma is stored in the blast freezer within an hour of arrival. Image: Steve Brown/DC Thomson.

It has a shelf life of 12 months once frozen; however, it needs to be used within 24 hours after thawing.

Senior biomedical scientist Lesley Macdonald slowly thawing fresh frozen plasma.
Senior biomedical scientist Lesley Macdonald slowly thawing fresh frozen plasma. Image: Steve Brown/DC Thomson.

The flexibility of plasma means it can also be used to make a variety of life-saving products and medicines.

By quick freezing, you preserve the clotting factor, and it can be used to treat patients who have major bleeding.

A worker placing platelets into storage at the Jack Copland Centre, Edinburgh.
A worker placing platelets into storage at the Jack Copland Centre, Edinburgh. Image: Steve Brown/DC Thomson.

For The Courier’s Be Our Blood campaign we are asking people across Tayside, Fife and Stirling to register here to become a donor.

Every donation can save up to three lives, but less than 3% of eligible people in Scotland give blood.

SNBTS needs 500 more people to become a donor in our area this year alone.

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