Theresa May has suffered a humiliating defeat in the House of Commons after MPs rejected her Brexit deal.
The Prime Minister will now face a vote of no confidence in her government after the loss of the crucial vote by a massive 432 to 202.
The failure of Mrs May to convince MPs to support her deal casts further doubt on the Brexit process and her own political future now hangs in the balance.
She now has until Monday to present a Brexit Plan B to parliament.
The vote had been dramatically postponed last month when Mrs May realised that it would not get through the Commons.
Mrs May has already survived an attempt from hard Brexiteers in her own Tory Party to express no confidence in her.
Mrs May is likely to survive the no confidence vote given Tory and DUP reluctance to do anything that would trigger a General Election that could see them lose power.
But further failure to make progress on Brexit will damage her irreparably.