Colchester reached the third round of the Carabao Cup for the first time in 15 years after beating Premier League Crystal Palace on penalties.
Norwich crashed out of the Carabao Cup following a shock 1-0 defeat at League Two Crawley.
Record-signing Ismaila Sarr made the perfect introduction to life at Vicarage Road as he helped Watford to their first win of the season with a 3-0 Carabao Cup success over Coventry.
Glenn Murray struck in stoppage time to earn Brighton a 2-1 win at Bristol Rovers in the Carabao Cup second round.
Sheffield United booked their place in the third round of the Carabao Cup with a 2-1 home win against Blackburn.
A second half strike from Michael Obafemi was enough to give Southampton a 1-0 win over Fulham and progress through to the third round of the Carabao Cup.
Aston Villa cruised into the third round of the Carabao Cup with a thumping 6-1 win over SkyBet League Two Crewe at Gresty Road.
Striker Yakou Meite scored twice as Sky Bet Championship side Reading fought back from 2-1 down to beat League Two Plymouth 4-2 at Home Park in the Carabao Cup second round.
Sabri Lamouchi claimed victory in his first east midlands derby as Nottingham Forest thumped old rivals Derby 3-0 in the Carabao Cup at the City Ground.
Jack Wilshere scored his first West Ham goal as Manuel Pellegrini’s side booked a Carabao Cup third-round spot with a 2-0 win at Newport.