Crewe will be without midfielder Josh Lundstram when they host Gillingham in Sky Bet League One on Tuesday.
The 21-year-old has suffered a stress fracture of the ankle and requires a scan to assess the extent of the damage.
Defender Olly Lancashire has been absent for a spell with a thigh problem but is closing in on a return.
Similarly, Donervon Daniels is nearing a comeback after missing four games with a muscular issue.
Gillingham manager Steve Evans is likely to be without Alex MacDonald, who was shown a red card during Saturday’s 2-0 loss to Sunderland.
Jacob Mellis is set to miss the rest of the season with cartilage damage, with Tom O’Connor sidelined with injury for a matter of weeks.
Jack Bonham will also be forced to sit the fixture out due to concussion but should return next week.
John Akinde recovered from a back spasm to feature at the weekend and could be involved again.