The road between Alyth and Meigle has been closed following a crash.
Emergency services were called to the B954 at 6.30am after a car overturned onto its roof.
The road was closed at the roundabout leading to the A926 from 7am until 8.30am.
A spokeswoman for Police Scotland said there were no serious injuries.
She said: “An RTC on the B954 was reported to us at 6.30am.
“A car is on its roof but there doesn’t appear to be any serious injuries.
“The road was closed at 7am.”